Freud, Jazz, PD, Prions

Freud on ideas without proofs, plus the quote from Aristotle, Kandel’s rehabilitation of Freud 

IDAGIO on Instagram: “‘Classical music is far from boring.’ We couldn’t agree more! Do you often meet people who claim that it is?”

IDAGIO on Instagram: “‘Classical music is far from boring.’ We couldn’t agree more! Do you often meet people who claim that it is?”

Jazz: 

https://www.instagram.com/p/DHlQBKfOq2z/?img_index=3&igsh=NTc4MTIwNjQ2YQ==

https://www.instagram.com/p/DHaoiUQMGsA/?igsh=NTc4MTIwNjQ2YQ==

https://www.instagram.com/stories/jazzphotoarchives/3595767111227087362?utm_source=ig_story_item_share&igsh=NTc4MTIwNjQ2YQ== 

Gen Z slang : https://www.instagram.com/reel/DHYfoSfK_W1/?igsh=NTc4MTIwNjQ2YQ==

“Anyone can become angry—that is easy,” [Aristotle] wrote in The Nicomachean Ethics. “But to be angry with the right person and to the right degree and at the right time and for the right purpose, and in the right way—that is not within everybody’s power and is not easy.”

We cannot do without men with the courage to think new things before they can prove them. < Freud.

“We must recollect that all of our provisional ideas in psychology will presumably one day be based on an organic substructure,”14 he wrote. In his book Beyond the Pleasure Principle, written in 1920, he continued: “The deficiencies in our description would probably vanish if we were already in a position to replace the psychological terms with physiological or chemical ones.… years of questions we have to put to it. They may be of a kind that will blow away the whole of our artificial structure of hypotheses.”

< Freud

  https://www.sciencedirect.com/science/article/abs/pii/S0197018624000871#preview-section-abstract

> Alpha-syn etc. Great article.

       

https://en.wikipedia.org/wiki/Proteinopathy

< The site of the brain affected (neurodegeneration) in the PD is not only substantia nigra but also locus coeruleus which is a major norepinephrine nucleus. Noradrenaline induces α-syn oligomers formation which is responsible for neurodegeneration in locus coeruleus. α-syn oligomerization is dependent on oxidation of noradrenaline

https://en.wikipedia.org/wiki/Birefringence#Optical_devices

https://en.wikipedia.org/wiki/Anti-%CE%B1-synuclein_drug

 https://pubmed.ncbi.nlm.nih.gov/22743090/

<  The gap between symptoms and pathology in Alzheimer’s disease has been explained by the hypothetical construct of “cognitive reserve”–a set of variables including education, intelligence, and mental stimulation which putatively allow the brain to adapt to-and hence mask–underlying pathologies by maintaining cognitive function despite underlying neural changes

     

https://en.wikipedia.org/wiki/Proteostasis

        

Resources for PD https://www.perplexity.ai/search/fd7da171-50ab-40fa-8802-ef5ae0891f30

 https://www.comparitech.com/blog/vpn-privacy/vpn-dutch-tv-abroad/

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