Neural Control of Walking in People with Parkinsonism

Neural Control of Walking in People with Parkinsonism

We adhere to a use of the term akinesia restricted to dysfunctions of movement initiation, ranging from delayed response to freezing or even total abolition of movement  < https://www.sciencedirect.com/topics/neuroscience/akinesia

Akinesia is just one side of the coin.  Basal ganglia, selection control etc.  By an actual patient

Was I  Born a Parky? Or Did I Become One?

< Results reveal, however, that various abnormalities within but also outside the motor and dopaminergic pathways might be associated with akinesia in PD patients. Notably, numerous yet poorly reproducible neural correlates were found in different brain regions supporting executive control by means of resting-state or task-based studies.

> We adhere to a use of the term akinesia restricted to dysfunctions of movement initiation, ranging from delayed response to freezing or even total abolition of movement. We also call for targeting more specific neural mechanisms of movement preparation and action triggering with more sophisticated behavioral designs/event-related neurofunctional analyses.

Symptom and syndrome are two terms commonly used in medical contexts to describe different aspects of a patient’s condition. A symptom refers to a specific indication or manifestation of an underlying disease or disorder that is experienced by the patient. It is often subjective and can vary from person to person. On the other hand, a syndrome is a collection of symptoms that occur together and are characteristic of a particular medical condition. It is a more comprehensive term that encompasses multiple symptoms and provides a broader understanding of the overall clinical picture. While symptoms help identify the presence of a problem, syndromes aid in diagnosing and categorizing specific diseases or disorders.

< https://thisvsthat.io/symptom-vs-syndrome

Disease vs. Disorder: What Is the Difference?

Accumulating evidence suggests that nicotine, a drug that stimulates  nicotinic acetylcholine receptors, may be of therapeutic value in Parkinson’s disease. Beneficial effects may be several-fold. One of these is a protective action against nigrostriatal damage. This possibility stems from the results of epidemiological studies that consistently demonstrate an inverse correlation between tobacco use and Parkinson’s disease. <

https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.2190

Twins: By Mikael Häggström.When using this image in external works, it may be cited as:Häggström, Mikael (2014). “Medical gallery of Mikael Häggström 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.008. ISSN 2002-4436. Public Domain.orBy Mikael Häggström, used with permission. – Own work, CC0, https://commons.wikimedia.org/w/index.php?curid=33081803

Risk factors for seborrhoeic dermatitis include poor immune function, Parkinson’s disease, and alcoholic pancreatitis < wiki seborrhoeic dermatitis

https://en.wikipedia.org/wiki/Frenkel_exercises

Purkinjje cells

Goal vs habitual action:

https://pubmed.ncbi.nlm.nih.gov/20944662/

Abstract

Progressive loss of the ascending dopaminergic projection in the basal ganglia is a fundamental pathological feature of Parkinson’s disease. Studies in animals and humans have identified spatially segregated functional territories in the basal ganglia for the control of goal-directed and habitual actions. In patients with Parkinson’s disease the loss of dopamine is predominantly in the posterior putamen, a region of the basal ganglia associated with the control of habitual behaviour. These patients may therefore be forced into a progressive reliance on the goal-directed mode of action control that is mediated by comparatively preserved processing in the rostromedial striatum. Thus, many of their behavioural difficulties may reflect a loss of normal automatic control owing to distorting output signals from habitual control circuits, which impede the expression of goal-directed action.

    

Garlicky Alfredo Beans Recipe

Garlicky Alfredo Beans Recipe

Kreyol: https://www.instagram.com/reel/DH6ZI7Wx8s2/?igsh=NTc4MTIwNjQ2YQ==  

I’ve never been very aural.

https://en.m.wikipedia.org/wiki/Coenzyme_Q10

发布了一篇小红书笔记,快来看吧! ? LwfcR2WCFCX1OyO ? http://xhslink.com/a/gZnILyYqaJl9,复制本条信息,打开【小红书】App查看精彩内容!

89%   10 being among the verbiage English and I have a wee smattering of Mandarin. 

Gitchy gitchy gou

2 Buddhawangwang发布了一篇小红书笔记,快来看吧! ? C2nHN06nCvDW1uX ? http://xhslink.com/a/fUFHTkgXtGN9,复制本条信息,打开【小红书】App查看精彩内容!

 

https://alteritas.net/pastis/edge-2/ > tumblr

 https://alteritas.net/pastis/edge-2/   

https://alteritas.net/pastis/tag/satori/page/2/ 

https://alteritas.net/pastis/tag/satori/page/2/ 

Deja vu vs d.v. all over again

Sestina vs sonnet

Isla mulheres 

I said proximity not propenquity

I was as close to a French existentialist as I could be in 1966, and moreover I was living in  France. Not Paris, where l imagined every French person aspired to be, but in Grenoble.

I had the extravagant privilege of a third year abroad, it was a privilege I had had to fight. In fact, this dream year went back to my adolescence. Since the age of 16…

There is nothing I agree with Donald Trump about, but sometimes he happens to agree with me. Case in point: the fashion of imposing your personal choice of pronouns on anyone else.  

Xi holds the best, actually the better cards in the game he’s playing wiith Trump

Edge 

Find earlier cersion 

Add line seasons  keeping as second line 

My Father … Dad’s course in life was fixed by his own father’s.. 

Liiterary but also digital

https://www.theatlantic.com/culture/archive/2020/04/20-undersung-crime-shows-to-watch-in-quarantine/610387/?gift=KKKlYTXEEqlHqE1fxXU8Y68BMZutsOXxLlnjhu7m_h4&utm_source=copy-link&utm_medium=social&utm_campaign=share

Blueberry soup

I’m not much for speculative fiction but was drawn into this book by its spurious use of neural science (the protag has two thalami) and  by its topicality: violation of Canadian sovereignty, a rogue VP, the 25th Amendment. It finishes with a nuc… WAIT! NO SPOILERS!. 

It was Good Friday so we took Sofie out for a fancy seafood meal. She’s the Mom of a good friend who has become a friend herself. She snapped the first shot, which I love. ThenI took the other two, the first while she was sending me the first  one.

            

MAGA is to WOKE just as WOKE is to MAGA.

Paliin-translation — English one way, French the other

Gustave Caillebotte: Painting Men | Getty Exhibitions

Gustave Caillebotte: Painting Men | Getty Exhibitions

Pont de L’Europe

Palindrome < From Ancient Greek παλίνδρομος (palíndromos, “running back again”), from πάλιν (pálin, “back, again, back again”) + δρόμος (drómos, “running, race, racecourse”). By surface analysis, palin- +‎ -drome (compare also velodrome and syndrome

Paliin-translation English one way, French the other

Music criticism should be to musicians what ornithology is to the birds  — Yuja Wang    

Anne Carson · Gloves on!

`Anne Carson · Gloves on!

Anne Carson · Poem: ‘In My Life as a Visiting Lecturer I Meet Various and Sundry People or,  Another Way to Think of This, Here Are All the Novels I Never Wrote and You Are Welcome to Them’

Anne Carson · Beware the man whose handwriting sways like a reed in the wind

 Sent to Red Dog and Jonathan

She’s got grace, in at least two senses of the word.

I fashion myself not so much as a critic, a word which has become problematic to some, rather as a commentator. Certainly nothing as serious as creator, let alone influencer.

Deficiency of some sort in the right fusiform gyrus of inferior …

Deficiency of some sort

I must have  a deficiency of some sort  in the right fusiform gyrus of the inferior medial temporal lobe of  my brain. People with damage to the front of that region are face-blind,

Bilish comedy < melodrama

Melancholy

Cold War Steve (@coldwarsteve) on X

Cold War Steve (@coldwarsteve) on X

The Factors that Induce or Overcome Freezing of Gait in Parkinson’s Disease – Rahman – 2008 – Behavioural Neurology – Wiley Online Library

The Factors that Induce or Overcome Freezing of Gait in Parkinson’s Disease

Send to Dogs.